Life Sciences
Speakman API Kilo Laboratory
PROJECT DESCRIPTION
This project involved the transformation of 2,300 sq. ft. of existing office space into a state-of-the-art Active Pharmaceutical Ingredient (API) Kilo Lab, supporting Eurofins Alphora’s growing High Potent Active Pharmaceutical Ingredient operations. The new lab was designed to enable advanced process development, scale-up, and GMP manufacturing activities in a controlled, high-containment environment. G architects led the project from initial planning through to construction.
Working in close collaboration with technical and quality assurance teams, the design team developed an efficient, highly functional layout that includes an API Kilo Lab, Quality Control lab, and associated support spaces. The scope encompassed full demolition of the existing space, followed by construction, equipment installation, start-up, and final commissioning - all completed on an accelerated 16-month schedule.
The lab was designed to meet stringent regulatory and operational standards for HPAPI handling, including features that support personnel safety, contamination control, and product integrity. Custom casework, specialized HVAC systems, and carefully planned material flows were integrated into the design to support cGMP compliance and seamless day-to-day operations.
Phil Goodfellow served as Partner-in-Charge, with Luke Kimmerer as Project Manager, bringing their deep sectoral expertise in pharmaceutical lab design and project execution to ensure a seamless and successful delivery.
CLIENT
Eurofins CDMO Alphora Inc.
VALUE
$3M
YEAR COMPLETE
2023
SCOPE
Renovation
Programming Validation and Test-Fit Studies
Full Prime Consulting Services for Design and Delivery
SIZE
1-storey, 5,500 ft²
PROJECT SCOPE
G architects led all stages of design and delivery for the 3,200 ft² adaptive reuse of George Brown College’s fifth-floor executive suite, including:
Space Planning and Fit-Out: Transformation of an outdated executive office into a modern academic workspace accommodating the Teaching & Learning Exchange (TLX) and the Office of Academic Excellence (OAE).
Programming and Design Development: Validation of space needs through test-fit studies, stakeholder workshops, and design refinement to support collaboration and innovation in teaching and learning.
Systems Integration and Coordination: Upgrades to mechanical, electrical, and IT infrastructure to support specialized functions such as the Virtual Reality Lab, recording studio, and testing areas.
Documentation and Tender Preparation: Development of detailed construction documents and Class A cost estimates, ensuring alignment with project budgets and institutional standards.
Construction Administration: Oversight of construction under a stipulated sum contract, including site verification, consultant coordination, and phased implementation to meet the College’s schedule and operational requirements.
CHALLENGES AND ACCOMPLISHMENTS
The expansion of a live HPAPI laboratory required precise coordination, technical integration, and adherence to stringent containment protocols. The design team faced the challenge of extending existing systems—such as HVAC, process utilities, and exhaust—while maintaining regulatory compliance and minimizing disruption to adjacent active operations. G architects developed a mirrored design solution that ensured functional continuity, optimized lab performance, and maintained the facility’s high safety and quality standards. The API Kilo Lab renovation was delivered on an accelerated 16-month schedule, enabling safe and compliant HPAPI manufacturing supported by new mechanical, HVAC, and containment systems.
